It’s 19th Century Edinburgh the leading city in medical learning and the Edinburgh Medical College is running low on cadavers. William Burke (Simon Pegg) and William Hare (Andy Serkis) are two Irish entrepreneurs who realise the potential money to be made from the situation. The trouble is there are not many cadavers around that they can sell on to the Medical College. A problem for most people but nothing is going to stop these two from making a killing literally. Based on the true story of the famous murderers comes a comic take on the exploits of two men who would not be deterred from making money the best way they knew how.