Yitzhak ( ()) is a male first name, and is Hebrew for Isaac. Yitzhak may refer to:
People
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Isaac, one of the patriarchs of the Israelites
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Yitzhak ha-Sangari, rabbi who converted the Khazars to Judaism
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Yitzhak Aharonovich (born 1950), Israeli politician
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Yitzhak Apeloig (born 1944), Israeli computational chemistry professor and President of the Technion
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Yitzhak Arad (1926–2021), Israeli historian
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Yitzhak Ben-Aharon (1906–2006), Israeli politician
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Yitzhak Ben-Zvi (1884–1963), Israeli politician and President
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Yitzhak Danziger (1916–1977), Israeli sculptor
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Yitzhak Hatuel (born 1962), Israeli Olympic foil fencer
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Yitzhak Hofi (1927–2014), Israeli general
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Yitzhak Laor (born 1948), Israeli poet
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Yitzhak Mastai (born 1966), Israeli professor of chemistry
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Yitzhak Molcho (born 1945), Israeli lawyer
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Yitzhak Mordechai (born 1944), Israeli general and politician
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Yitzhak Navon (1921–2015), Israel politician and President
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Vicky Peretz (1953–2021), Israeli Olympic footballer
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Yitzhak Rabin (1922–1995), Israeli politician and Prime Minister
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Yitzhak Sadeh (1890–1952), Israeli general
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Yitzhak Schwartz, birth name of Irving Fields (1915–2016), American pianist and composer
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Yitzhak Shamir (1915–2012), Israeli politician and Prime Minister
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Yitzhak Tshuva (born 1948), Israeli businessman
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Yitzhak Y. Melamed (born 1968), Israeli-American philosophy professor
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Yitzhak Yosef (born 1952), Israeli chief rabbi
Fiction
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Yitzhak, fictional character in the musical and film Hedwig and the Angry Inch
See also