Upadhyay is a surname. Notable people who bear the name include:
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Amar Upadhyay (born 1976), Indian model, film and television actor
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Amod Prasad Upadhyay (born 1936), Nepalese social worker and politician
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Ayodhya Prasad Upadhyay (1865–1947), writer of Hindi literature
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Brahmabandhav Upadhyay (1861–1907), Bengali Brahmin, nephew of the Indian freedom-fighter Kalicharan Banerjee
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Chabilal Upadhyaya (1882–1980), Nepali Brahmin(Bahun), First President (Selected) of Assam Pradesh Congress Committee
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Chintan Upadhyay (born 1972), Indian artist, accused of a 2015 murder
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Chandrika Prasad Upadhyay (born 1950), Indian politician
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Deendayal Upadhyaya (1916–1968), Indian politician and thinker, co-founder of the political party Bharatiya Jana Sangh
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Darshan Upadhyaya (born 1994), Canada-born American esports player
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Harilal Upadhyay (1916–1994), Gujarati author
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Hema Upadhyay (1972–2015), Indian artist who lived and worked in Mumbai, India since 1998
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Kedar Nath Upadhyay, Chief Justice of Nepal at Supreme Court
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Kishore Upadhyaya (born 1958), Indian politician
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Krishnakant Upadhyay (born 1986), cricketer from Uttar Pradesh
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Lalit Upadhyay (born 1993), Indian field hockey player, part of Indian national team
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Moxila A. Upadhyaya, Indian-born U.S. Magistrate Judge
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Munishwar Dutt Upadhyay (1898–1983), Indian politician and statesman, leader in the Indian independence movement
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Purushottam Upadhyay (1934–2024), Indian musician, singer and composer
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Ram Kinkar Upadhyay (1924–2002), scholar on Indian scriptures and a recipient of Padma Bhushan
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Ramveer Upadhyay (1957–2022), Minister for Transport of Uttar Pradesh in 1997, Minister for Power, Medical Education (2002–2003), Minister for Power (2007–2012)
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Samrat Upadhyay (born 1964), Nepalese writer who writes in English
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Satish Upadhyay (born 1962), the President of the Delhi Unit of Bharatiya Janata Party (BJP)
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Seema Upadhyay (born 1965), Indian politician, belonging to Bahujan Samaj Party
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Shailendra Kumar Upadhyay (1929–2011), Nepalese diplomat and politician
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Shrikrishna Upadhyay (born 1945), Nepalese economist
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Umesh Upadhyay (born 1960), Indian television journalist and media executive
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Vikas Upadhyay (born 1975), Indian politician, general secretary for All India Youth Congress
