Product Code Database
The trifluoromethoxy group is the chemical group –O–. It can be seen as a methoxy group –O– whose hydrogen atoms are replaced by fluorine atoms; or as a trifluoromethyl group attached to the rest of the molecule by a bridging oxygen atom; either leads to viable syntheses. Synthetic Approaches to Trifluoromethoxy-Substituted Compounds A. Tlili, F. Toulgoat, T. Billard, Angew. Chem. Int. Ed. 2016, 55, 11726–11735; Compounds having this functional group are of some relevance as pharmaceuticals. One example is riluzole.
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