Phenylpyrazole insecticides are a class of chemically-related broad-spectrum
insecticides.
The chemical structures of these insecticides are characterized by a central
pyrazole ring with a
phenyl group attached to one of the nitrogen atoms of the pyrazole.
History
Phenylpyrazole insecticides were developed in response to increasing pesticide resistance to other chemicals. Now, along with
, they are some of the most widely-used pesticides.
Mode of Action
Phenylpyrazole insecticides function by blocking GABA-gated chloride channels in insects (IRAC group 2B).
Mammals do not have this type of chloride channel, making them much less susceptible to its effects. However, they do have the capacity to disrupt
Epithelium in the human intestine and adversely impact human health.
Examples
Examples include:
External links
