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Exopeptidase
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An exopeptidase is any that the cleavage of the terminal (or the penultimate) ; the process releases a single , or a from the peptide chain.

(1992). 9788005010767, Alfa.
Depending on whether the amino acid is released from the amino or the carboxy terminal ( or ), an exopeptidase is further classified as an aminopeptidase or a carboxypeptidase, respectively. Thus, an , an enzyme in the of the , will cleave a single amino acid from the amino terminal, whereas , which is a present in , will cleave a single amino acid from the carboxylic end of the peptide.

Some examples of exopeptidases include:

  • Carboxypeptidase A - cleaves C-terminal Phe, Tyr, Trp, or Leu
  • Carboxypeptidase B - cleaves C-terminal Lys or Arg
  • - cleaves any N-terminal amino acid
  • - cleaves N-terminal Pro from dipeptides
  • - cleaves C-terminal Pro from dipeptides


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