Erinacines are natural substances isolated from the mycelium of Hericium erinaceus (lion's mane mushroom). They belong to the group of cyathin (erinacines A–K, P, Q, S, U) and are subjects of pharmacological research, which largely focuses on the benefits of erinacine on the brain.
Erinacine A
Erinacine A, isolated from the cultured mycelia of
Hericium erinaceus, the main representative of this compounds group, has an enhancing effect on nerve growth factor synthesis
in vitro.
It also increases the levels of
in the central nervous system of rats.
Erinacine A has also been prepared by total synthesis.
Erinacine E
Erinacine E is a kappa opioid receptor agonist.
Erinacine S
Erinacine S has been shown to cross the blood–brain barrier
In vivo, highlighting the bioavailability of this compound in the brain.
Further reading
