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A defoliant is any Herbicide chemical sprayed or dusted on plants to cause their Leaf to fall off. Defoliants are widely used for the selective removal of weeds in managing croplands and lawns. Worldwide use of defoliants, along with the development of other herbicides and , allowed for the Green Revolution, an increase in agricultural production in mid-20th century. Defoliants have also been used in warfare as a means to deprive an enemy of food crops and/or hiding cover, most notably by the United Kingdom during the Malayan Emergency and the United States in the Vietnam War. Defoliants were also used by Indonesian forces in various internal security operations. (2025). 081221711X, University of Pennsylvania Press. 081221711X
Defoliants have a practical use in the harvesting of certain crops, particularly cotton, in the United States as well as a number of other cotton-producing countries. The use of defoliants aids in the effective harvesting of cotton and finer lint quality. The effectiveness of defoliant use in cotton harvesting depends on the type of defoliant(s) used, the number of applications, the amount applied, and environmental variables. Common harvest-aiding chemical defoliants include tribufos, dimethipin, and thidiazuron. According to a 1998 report by the U.S. Department of Agriculture National Agricultural Statistics Service (NASS), tribufos and thidiazuron accounted for 60% of crop area that was treated by defoliants during that crop year.NASS (1999). Agricultural Chemical Usage 1998 Field Crops Summary. Washington, D.C.: U. S. Department of Agriculture National Agricultural Statistics and Economic Research Service. pg 141.
A published study in the Journal of Agricultural and Food Chemistry reported that through successive surface runoff events in defoliated cotton fields, defoliant concentrations decreased exponentially within the test area and could negatively affect marine life in the runoff zones.
Agent Orange, a defoliant used by the United Kingdom during the Malayan Emergency in the 1950s and the United States during the Vietnam War to defoliate regions of Vietnam from 1961 to 1971, has been linked to several long-term health issues. Agent Orange contains a mixture of 2,4-D and 2,4,5-T as well as dioxin contaminants. Members of the Air Force Ranch Hand and the Chemical Corps who served in the Vietnam War were occupationally exposed to Agent Orange have a higher incidence of diabetes, heart disease, hypertension, and chronic respiratory diseases.
Among other occupations, farmers are at a significantly higher risk of developing Alzheimer's disease due to a greater chance of defoliant exposure.
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