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   » » Wiki: Chronotropic
Tag Wiki 'Chronotropic'.
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Chronotropic effects (from chrono-, meaning time, and tropos, "a turn") are those that change the .

Chronotropic may change the rate and by affecting the electrical conduction system of the heart and the nerves that influence it, such as by changing the the . Positive chronotropes increase heart rate; negative chronotropes decrease heart rate.

A affects atrioventricular node (AV node) conduction. A positive dromotrope increases AV nodal conduction, and a negative dromotrope decreases AV nodal conduction. A is an agent that affects diastolic relaxation.

Many positive affect preload and .


Positive chronotropes


Negative chronotropes
Chronotropic variables can be considered in systolic myocardial left and right sides. Left sided systolic chronotropy can be appreciated as Aortic Valve open to close time. Right sided variables are represented by pulmonary valve open to close time. Inverted as diastolic chronotropy, the variables are aortic valve close to open and pulmonic close to open time. Pharmaceutical manipulation of chronotropic properties was perhaps first appreciated by the introduction of , though it turns out that digitalis has an effect rather than a chronotropic effect.

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