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, a group of intracellular parasites, have life cycle stages that allow them to survive the wide variety of environments they are exposed to during their complex life cycle. Each stage in the life cycle of an organism is typified by a cellular variety with a distinct morphology and biochemistry.
Not all apicomplexa develop all the following cellular varieties and division methods. This presentation is intended as an outline of a hypothetical generalised apicomplexan organism.
Merogony is an asexually reproductive process of apicomplexa. After infecting a host cell, a trophozoite (see glossary below) increases in size while repeatedly replicating its Cell nucleus and other organelles. During this process, the organism is known as a ' or '. Cytokinesis next subdivides the multinucleated schizont into numerous identical daughter cells called merozoites (see glossary below), which are released into the blood when the host cell ruptures. Organisms whose life cycles rely on this process include Theileria, Babesia, Plasmodium, and Toxoplasma gondii.
Sporogony is a type of sexual and asexual reproduction. It involves karyogamy, the formation of a zygote, which is followed by meiosis and multiple fission. This results in the production of sporozoites.
Other forms of replication include ' and '.
Endodyogeny is a process of asexual reproduction, favoured by parasites such as Toxoplasma gondii. It involves an unusual process in which two daughter cells are produced inside a mother cell, which is then consumed by the offspring prior to their separation. (1994). 9780521428118, Cambridge University Press. ISBN 9780521428118
Endopolygeny is the division into several organisms at once by internal budding.
A (G. meros, part of + zōon, animal) is the result of merogony that takes place within a host cell. During this stage, the parasite infects the host's cells and then replicates its own nucleus and induces cell segmentation in a form of asexual reproduction. In coccidiosis, merozoites form the first phase of the internal life cycle of coccidian. In the case of Plasmodium, merozoites infect red blood cells and then rapidly reproduce asexually. The red blood cell host is destroyed by this process, which releases many new merozoites that go on to find new blood-borne hosts. Merozoites are motile. Before schizogony, the merozoite is also known as the schizozoite.
A (Greek language gametēs, partner + kytos, cell) is a name given to a parasite's gamete-forming cells. A male gametocyte divides to give many flagellated , whereas the female gametocyte differentiates to a macrogamete.
An (G. ōon, egg + kinētos, motile) is a fertilised zygote capable of moving spontaneously. It penetrates epithelial cells lining the midgut of to form a thick-walled structure known as an oocyst under the mosquito's outer gut lining. Ookinetes are motile and they move by gliding motility.
A (G. trophē, nourishment + zōon, animal) is the activated, intracellular feeding stage in the apicomplexan life cycle. After gorging itself on its host, the trophozoite undergoes schizogony and develops into a schizont, later releasing merozoites.
A hypnozoite (G. hypnos, sleep + zōon, animal) is a quiescent parasite stage that is best known for its "... probable association with latency and relapse in human malarial infections caused by Plasmodium ovale and P. vivax". Hypnozoites are directly sporozoite-derived.
A (G. bradys, slow + zōon, animal) is a sessile, slow-growing form of zoonosis such as Toxoplasma gondii, among others responsible for parasitic infections. In chronic (latent) toxoplasmosis, bradyzoites microscopically present as clusters enclosed by an irregular crescent-shaped wall () in infected muscle and brain tissues. Also known as a bradyzoic merozoite.
A (G. tachys, fast + zōon, animal), contrasting with a bradyzoite, is a form typified by rapid growth and replication. Tachyzoites are the motile forms of those which form tissue , such as Toxoplasma and Sarcocystis. Typically infecting cellular , tachyzoites divide by endodyogeny and endopolygeny. Also known as a tachyzoic merozoite (same journal reference as for "bradyzoic merozoite", above).
An (G. ōon, egg + kystis, bladder) is a hardy, thick-walled spore, able to survive for lengthy periods outside a host. The zygote develops within the spore, which acts to protect it during transfer to new hosts. Organisms that create oocysts include Eimeria, Isospora, Cryptosporidium, and Toxoplasma.
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