Geranylgeranyl pyrophosphate

 ( Pyrophosphate Esters ) 

Geranylgeranyl pyrophosphate is an intermediate in the biosynthesis of and di.

It is also a precursor to geranylgeranylated proteins, which is its primary use in human cells.

It is formed from farnesyl pyrophosphate by the addition of an isoprene unit from isopentenyl pyrophosphate.

In Drosophila, geranylgeranyl pyrophosphate is synthesised by HMG-CoA encoded by the Columbus gene. Geranylgeranyl pyrophosphate is utilised as a chemoattractant for migrating that have traversed the midgut epithelia. The attractant signal is produced at the precursors, directing the germ cells to these sites, where they will differentiate into eggs and spermatozoa (sperm).

• Farnesyl pyrophosphate
• Geranylgeraniol
• Geranyl pyrophosphate