Anthrax immune globulin, sold under the brand name Anthrasil, is a human immune globulin that is used in combination with antibiotics to treat anthrax.
Preparation
Anthrax immune globulin is prepared from the
blood plasma of
blood donor who have been vaccinated against anthrax.
Safety and efficacy testing
Due to the ethical and feasibility concerns with testing the efficacy of anthrax immune globulin in humans, it was tested in rabbits and monkeys under the FDA's animal efficacy rule. Following efficacy testing, anthrax immune globulin was tested for safety in human volunteers, where the most common side effects were headache, back pain, nausea and infusion site pain and swelling.
