Treatment and Prevention of Malaria Milestones in Drug Therapy 1 Binding: Hardcover Publisher: Springer Verlag Publish Date: 2012/01/05 Language: ENGLISH Pages: 315 Dimensions: 9.25 x 6.25 x 0.75 Weight: 1.30 ISBN-13: 9783034604796
It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.