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Selective Estrogen Receptor Modulators: Research And Clinical Applications
 (

ISBN 9780896039124
REGISTERED: 12/08/17
UPDATED: 10/26/20
Selective Estrogen Receptor Modulators: Research And Clinical Applications

Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs


Specifications
  • Selective Estrogen Receptor Modulators: Research And Clinical Applications available on January 16 2017 from Indigo for 375.95
  • ISBN bar code 9780896039124 ξ2 registered October 12 2016
  • ISBN bar code 9780896039124 ξ1 registered February 04 2015
  • Product category is Book

  • # 978089603912

The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.


References
    ^ Contemporary Endocrinology Ser.: Selective Estrogen Receptor Modulators : Research and Clinical Applications (2002, Hardcover) (revised Oct 2016)
    ^ Selective Estrogen Receptor Modulators: Research And Clinical Applications Indigo. (revised Jan 2017)

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