Non-corn based ascorbic acid with bioflavonoid concentrate Hesperidin and mixed bioflavonoids help protect ascorbic acid from oxidation, thus extending vitamin C?s capacity as an antioxidant. Ascorbic acid participates in the formation of collagen and is required for the maintenance of connective tissues such as cartilage and ligaments. Vitamin C, as it occurs in nature, is always accompanied by rutin, hesperidin and citrus bioflavonoids.